Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches

Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches

Abstract Current therapeutic strategies against bacterial infections focus on reduction of pathogen load using antibiotics; however, stimulation of host tolerance to infection in the presence of pathogens might offer an alternative approach. Computational transcriptomics and Xenopus laevis embryos a...

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Bibliographic Details
Main Authors: Megan M. Sperry, Richard Novak, Vishal Keshari, Alexandre L. M. Dinis, Mark J. Cartwright, Diogo M. Camacho, Jean‐François Paré, Michael Super, Michael Levin, Donald E. Ingber
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Advanced Science
Subjects:
drug repurposing
host response
infection
sepsis
tolerance
Online Access:https://doi.org/10.1002/advs.202200222

Internet

https://doi.org/10.1002/advs.202200222

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