Liver saturated fat content associates with hepatic DNA methylation in obese individuals
Abstract Background Accumulation of saturated fatty acids (SFAs) in the liver is known to induce hepatic steatosis and inflammation causing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Although SFAs have been shown to affect the epigenome in whole blood, pancre...
Main Authors: | Ratika Sehgal, Alexander Perfilyev, Ville Männistö, Jyrki Ågren, Emma Nilsson, Pirjo Käkelä, Charlotte Ling, Vanessa D. de Mello, Jussi Pihlajamäki |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | Clinical Epigenetics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13148-023-01431-x |
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