Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells

Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.

Bibliographic Details
Main Authors: Yuchen Liu, Weiren Huang, Zhiming Cai
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19314-7