The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data.

The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data.

We consider the feasibility of reusing existing control data obtained in genetic association studies in order to reduce costs for new studies. We discuss controlling for the population differences between cases and controls that are implicit in studies utilizing external control data. We give theore...

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Bibliographic Details
Main Authors: Gary K Chen, Robert C Millikan, Esther M John, Christine B Ambrosone, Leslie Bernstein, Wei Zheng, Jennifer J Hu, Stephen J Chanock, Regina G Ziegler, Elisa V Bandera, Brian E Henderson, Christopher A Haiman, Daniel O Stram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2932740?pdf=render

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http://europepmc.org/articles/PMC2932740?pdf=render

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