Reliable Genetic Correlation Estimation via Multiple Sample Splitting and Smoothing
In this paper, we aim to investigate the problem of estimating the genetic correlation between two traits. Instead of making assumptions about the distribution of effect sizes of the genetic factors, we propose the use of a high-dimensional linear model to relate a trait to genetic factors. To estim...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
|
| Series: | Mathematics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-7390/11/9/2163 |