Pulling back the mitochondria’s iron curtain

Abstract Mitochondrial functionality and cellular iron homeostasis are closely intertwined. Mitochondria are biosynthetic hubs for essential iron cofactors such as iron-sulfur (Fe-S) clusters and heme. These cofactors, in turn, enable key mitochondrial pathways, such as energy and metabolite product...

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Bibliographic Details
Main Authors: Shani Ben Zichri- David, Liraz Shkuri, Tslil Ast
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Metabolic Health and Disease
Online Access:https://doi.org/10.1038/s44324-024-00045-y