A reappraisal of the mechanism by which plant sterols promote neutral sterol loss in mice.

Dietary plant sterols (PS) reduce serum total and LDL-cholesterol in hyperlipidemic animal models and in humans. This hypocholesterolemic effect is generally ascribed to inhibition of cholesterol absorption. However, whether this effect fully explains the reported strong induction of neutral sterol...

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Bibliographic Details
Main Authors: Gemma Brufau, Folkert Kuipers, Yuguang Lin, Elke A Trautwein, Albert K Groen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3128081?pdf=render