Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome

Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a multifactorial chronic gastrointestinal disorder characterized by inflammation and immune response. In this context, NLRP3 over-activation is associated with a breakdown of enteric-immune balance related to IBS-D. The aim of this study was t...

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Bibliographic Details
Main Authors: Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Alessia Filippone, Irene Paterniti, Emanuela Esposito, Michela Campolo
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
IBS-D
inflammasome
NLRP3
NF-κB
stress
intestinal permeability
Online Access:https://www.mdpi.com/2227-9059/8/11/519

Internet

https://www.mdpi.com/2227-9059/8/11/519

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