PTEN and AKT/GSK-3β/CRMP-2 signaling pathway are involved in neuronal apoptosis and axonal injury in early brain injury after SAH in rats

PTEN and AKT/GSK-3β/CRMP-2 signaling pathway are involved in neuronal apoptosis and axonal injury in early brain injury after SAH in rats

In early brain injury (EBI) after subarachnoid hemorrhage (SAH), white matter (WM) axonal injury plays a key role in the prognosis of the disease. The purpose of this study was to investigate the effects of phosphatase and tensin homolog deleted on chromosome ten (PTEN) on axonal injury and neuronal...

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Bibliographic Details
Main Authors: Hong Chen, Chao Zhou, Jianfeng Zheng, Zhaosi Zhang, Yongbing Deng, Chongjie Cheng, Zongduo Guo, Gang Huo, Cheng Yin, Xiaochuan Sun
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Genes and Diseases
Subjects:
AKT/GSK-3β/CRMP-2 pathway
Axonal injury
Early brain injury
Neuronal apoptosis
PTEN
Subarachnoid hemorrhage
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300672

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http://www.sciencedirect.com/science/article/pii/S2352304220300672

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