Integrative single-cell RNA-seq analysis of vascularized cerebral organoids

Abstract Background Cerebral organoids are three-dimensional in vitro cultured brains that mimic the function and structure of the human brain. One of the major challenges for cerebral organoids is the lack of functional vasculature. Without perfusable vessels, oxygen and nutrient supplies may be in...

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Bibliographic Details
Main Authors: Yuya Sato, Toru Asahi, Kosuke Kataoka
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-023-01711-1