Involvement of Kv1.5 protein in oxidative vascular endothelial cell injury.

Endothelial injury related to oxidative stress is a key event in cardiovascular diseases, such as hypertension and atherosclerosis. The activation of the redox-sensitive Kv1.5 potassium channel mediates mitochondrial reactive oxygen species (ROS)-induced apoptosis in vascular smooth muscle cells and...

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Bibliographic Details
Main Authors: Wen-Liang Chen, Xiong-Qing Huang, Li-Yan Zhao, Jie Li, Jian-Wen Chen, Ying Xiao, Yun-Ying Huang, Jie Liu, Guan-Lei Wang, Yong-Yuan Guan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504089?pdf=render