Protein degradation: expanding the toolbox to restrain cancer drug resistance

Abstract Despite significant progress in clinical management, drug resistance remains a major obstacle. Recent research based on protein degradation to restrain drug resistance has attracted wide attention, and several therapeutic strategies such as inhibition of proteasome with bortezomib and prote...

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Bibliographic Details
Main Authors: Hui Ming, Bowen Li, Jingwen Jiang, Siyuan Qin, Edouard C. Nice, Weifeng He, Tingyuan Lang, Canhua Huang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-023-01398-5