Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus

Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. While its etiology remains elusive, current understanding suggests a multifactorial process with contributions by genetic, immunologic, hormonal, and environmental factors. A hypothesis that combines several of these factors p...

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Bibliographic Details
Main Authors: Kennedy C. Ukadike, Tomas Mustelin
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
systemic lupus erythematosus
retroelements
L1
LINE-1
reverse transcriptase
type I interferons
Online Access:https://www.mdpi.com/2077-0383/10/4/856

Internet

https://www.mdpi.com/2077-0383/10/4/856

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