Determinants of translation efficiency and accuracy

Abstract Proper functioning of biological cells requires that the process of protein expression be carried out with high efficiency and fidelity. Given an amino‐acid sequence of a protein, multiple degrees of freedom still remain that may allow evolution to tune efficiency and fidelity for each gene...

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Bibliographic Details
Main Authors: Hila Gingold, Yitzhak Pilpel
Format: Article
Language:English
Published: Springer Nature 2011-04-01
Series:Molecular Systems Biology
Online Access:https://doi.org/10.1038/msb.2011.14