Time- and Concentration-Dependent Adverse Effects of Paclitaxel on Non-Neuronal Cells in Rat Primary Dorsal Root Ganglia

Paclitaxel is a chemotherapeutic agent used to treat a wide range of malignant tumors. Although it has anti-tumoral properties, paclitaxel also shows significant adverse effects on the peripheral nervous system, causing peripheral neuropathy. Paclitaxel has previously been shown to exert direct neur...

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Bibliographic Details
Main Authors: Amira Elfarnawany, Faramarz Dehghani
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/11/7/581