Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs
Since 2003, rare inborn errors of human type I IFN immunity have been discovered, each underlying a few severe viral illnesses. Autoantibodies neutralizing type I IFNs due to rare inborn errors of autoimmune regulator (AIRE)–driven T cell tolerance were discovered in 2006, but not initially linked t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical Investigation
2023-02-01
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| Series: | The Journal of Clinical Investigation |
| Online Access: | https://doi.org/10.1172/JCI166283 |