In vitro and in silico lipoxygenase inhibition studies and antimicrobial activity of pyrazolyl-phthalazine-diones

In vitro and in silico lipoxygenase inhibition studies and antimicrobial activity of pyrazolyl-phthalazine-diones

The series of pyrazolyl-phthalazine-dione derivatives (PPDs) was subjected to evaluation of their in vitro lipoxygenase (LOX) inhibition and antimicrobial activities. Results obtained for LOX inhibition activities of PPDs showed that all compounds exhibit good to excellent activity, whereby compound...

Full description

Bibliographic Details
Main Authors: Milovanović Vesna M., Petrović Zorica D., Petrović Vladimir P., Simijonović Dušica, Mladenović Milan, Tomašević Nevena, Čomić Ljiljana R., Radojević Ivana D.
Format: Article
Language:English
Published: University of Kragujevac, Faculty of Science 2021-01-01
Series:Kragujevac Journal of Science
Subjects:
pyrazolyl-phthalazine-dione derivatives
anti-inflammatory activity
molecular docking
antimicrobial activity
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2021/1450-96362143035M.pdf

Internet

https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2021/1450-96362143035M.pdf

Similar Items