Sangivamycin is highly effective against SARS-CoV-2 in vitro and has favorable drug properties

Sangivamycin is highly effective against SARS-CoV-2 in vitro and has favorable drug properties

Sangivamycin is a nucleoside analog that is well tolerated by humans and broadly active against phylogenetically distinct viruses, including arenaviruses, filoviruses, and orthopoxviruses. Here, we show that sangivamycin is a potent antiviral against multiple variants of replicative severe acute res...

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Bibliographic Details
Main Authors: Ryan P. Bennett, Elena N. Postnikova, Brett P. Eaton, Yingyun Cai, Shuiqing Yu, Charles O. Smith, Janie Liang, Huanying Zhou, Gregory A. Kocher, Michael J. Murphy, Harold C. Smith, Jens H. Kuhn
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-01-01
Series:JCI Insight
Subjects:
COVID-19
Therapeutics
Online Access:https://doi.org/10.1172/jci.insight.153165

Internet

https://doi.org/10.1172/jci.insight.153165

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