An Emerging Allee Effect Is Critical for Tumor Initiation and Persistence.

Tumor cells develop different strategies to cope with changing microenvironmental conditions. A prominent example is the adaptive phenotypic switching between cell migration and proliferation. While it has been shown that the migration-proliferation plasticity influences tumor spread, it remains unc...

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Bibliographic Details
Main Authors: Katrin Böttger, Haralambos Hatzikirou, Anja Voss-Böhme, Elisabetta Ada Cavalcanti-Adam, Miguel A Herrero, Andreas Deutsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004366