RSPO2 as Wnt signaling enabler: Important roles in cancer development and therapeutic opportunities
R-spondins are secretory proteins localized in the endoplasmic reticulum and Golgi bodies and are processed through the secretory pathway. Among the R-spondin family, RSPO2 has emanated as a novel regulator of Wnt signaling, which has now been acknowledged in numerous in vitro and in vivo studies. C...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2024-03-01
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Series: | Genes and Diseases |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304223000338 |