Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy.

<h4>Background</h4>The simultaneous accumulation of different misfolded proteins in the central nervous system is a common feature in many neurodegenerative diseases. In most cases, co-occurrence of abnormal deposited proteins is observed in different brain regions and cell populations,...

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Main Authors: Nahuai Badiola, Rita Machado de Oliveira, Federico Herrera, Cristina Guardia-Laguarta, Susana A Gonçalves, Marta Pera, Marc Suárez-Calvet, Jordi Clarimon, Tiago Fleming Outeiro, Alberto Lleó
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039514/?tool=EBI