Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives

Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives

Abstract Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triazole moiety (7a-e) and aryl triazole bearing group...

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Bibliographic Details
Main Authors: Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohammad Hasan Jamei, Alireza Poustforoosh, Somayeh Nazari, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edraki
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Chemistry
Subjects:
Imidazopyridine
1,2,3-triazole ring
Carbohydrazide
Cytotoxic activity
Molecular docking
Molecular dynamics
Online Access:https://doi.org/10.1186/s13065-023-01073-3

Internet

https://doi.org/10.1186/s13065-023-01073-3

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