Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease

Rapid release of calcium from internal stores via ryanodine receptors (RyRs) is one of the fastest types of cytoplasmic second messenger signalling in excitable cells. In the heart, rapid summation of the elementary events of calcium release, 'calcium sparks', determine the contraction of...

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Bibliographic Details
Main Authors: Miriam E. Hurley, Ed White, Thomas M. D. Sheard, Derek Steele, Izzy Jayasinghe
Format: Article
Language:English
Published: The Royal Society 2023-05-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.230045