Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease
Rapid release of calcium from internal stores via ryanodine receptors (RyRs) is one of the fastest types of cytoplasmic second messenger signalling in excitable cells. In the heart, rapid summation of the elementary events of calcium release, 'calcium sparks', determine the contraction of...
Main Authors: | Miriam E. Hurley, Ed White, Thomas M. D. Sheard, Derek Steele, Izzy Jayasinghe |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2023-05-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.230045 |
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