CPAP enhances and maintains chronic inflammation in hepatocytes to promote hepatocarcinogenesis
Abstract Chronic and persistent inflammation is a well-known carcinogenesis promoter. Hepatocellular carcinoma (HCC) is one of the most common inflammation-associated cancers; most HCCs arise in the setting of chronic inflammation and hepatic injury. Both NF-κB and STAT3 are important regulators of...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-10-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04295-2 |