CPAP enhances and maintains chronic inflammation in hepatocytes to promote hepatocarcinogenesis

Abstract Chronic and persistent inflammation is a well-known carcinogenesis promoter. Hepatocellular carcinoma (HCC) is one of the most common inflammation-associated cancers; most HCCs arise in the setting of chronic inflammation and hepatic injury. Both NF-κB and STAT3 are important regulators of...

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Bibliographic Details
Main Authors: Ruo-Yu Chen, Chia-Jui Yen, Yih-Jyh Lin, Ju-Ming Wang, Ting-Fen Tasi, Yu-Chuan Huang, Yao-Wen Liu, Hung-Wen Tsai, Ming-Hao Lee, Liang-Yi Hung
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04295-2