6-Gingerol regulates triglyceride and cholesterol biosynthesis to improve hepatic steatosis in MAFLD by activating the AMPK-SREBPs signaling pathway

6-Gingerol regulates triglyceride and cholesterol biosynthesis to improve hepatic steatosis in MAFLD by activating the AMPK-SREBPs signaling pathway

Excessive synthesis of triglycerides and cholesterol accelerates the progression of hepatic steatosis in metabolic-associated fatty liver disease (MAFLD). However, the precise mechanism by which 6-gingerol mitigates hepatic steatosis in MAFLD model mice has yet to be fully understood. The present st...

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Bibliographic Details
Main Authors: Qingsong Xia, Fuer Lu, Yu Chen, Jingbin Li, Zhaoyi Huang, Ke Fang, Meilin Hu, Yujin Guo, Hui Dong, Lijun Xu, Jing Gong
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
6-Gingerol
MAFLD
Triglyceride biosynthesis
Cholesterol biosynthesis
SREBPs
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223018589

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http://www.sciencedirect.com/science/article/pii/S0753332223018589

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