Expression and mechanisms of interferon-stimulated genes in viral infection of the central nervous system (CNS) and neurological diseases

Interferons (IFNs) bind to cell surface receptors and activate the expression of interferon-stimulated genes (ISGs) through intracellular signaling cascades. ISGs and their expression products have various biological functions, such as antiviral and immunomodulatory effects, and are essential effect...

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Bibliographic Details
Main Authors: Rui Lang, Huiting Li, Xiaoqin Luo, Cencen Liu, Yiwen Zhang, ShunYu Guo, Jingyi Xu, Changshun Bao, Wei Dong, Yang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1008072/full