Molecular Detection of <i>Borrelia</i> Bacteria in Cerebrospinal Fluid-Optimisation of Pre-Analytical Sample Handling for Increased Analytical Sensitivity

Molecular Detection of <i>Borrelia</i> Bacteria in Cerebrospinal Fluid-Optimisation of Pre-Analytical Sample Handling for Increased Analytical Sensitivity

The main tools for clinical diagnostics of Lyme neuroborreliosis (LNB) are based on serology, i.e., detection of antibodies in cerebrospinal fluid (CSF). In some cases, PCR may be used as a supplement, e.g., on CSF from patients with early LNB. Standardisation of the molecular methods and systematic...

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Bibliographic Details
Main Authors: Malin Lager, Peter Wilhelmsson, Andreas Matussek, Per-Eric Lindgren, Anna J. Henningsson
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Diagnostics
Subjects:
Lyme borreliosis
Lyme neuroborreliosis
polymerase chain reaction (PCR)
cerebrospinal fluid
clinical diagnostic
optimization
Online Access:https://www.mdpi.com/2075-4418/11/11/2088

Internet

https://www.mdpi.com/2075-4418/11/11/2088

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