PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting.

Plant-pathogenic Xanthomonas bacteria secrete transcription activator-like effectors (TALEs) into host cells, where they act as transcriptional activators on plant target genes to support bacterial virulence. TALEs have a unique modular DNA-binding domain composed of tandem repeats. Two amino acids...

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Bibliographic Details
Main Authors: Annett Erkes, Stefanie Mücke, Maik Reschke, Jens Boch, Jan Grau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007206