Influence of Carbon Nanotubes and Its Derivatives on Tumor Cells In Vitro and Biochemical Parameters, Cellular Blood Composition In Vivo

Influence of Carbon Nanotubes and Its Derivatives on Tumor Cells In Vitro and Biochemical Parameters, Cellular Blood Composition In Vivo

Abstract The aim of the proposed work was to analyze the toxicity of oxidized carbon nanotubes (CNTox), functionalized by doxorubicin (CNT-Dox) and fluorescein (CNT-FITC) on cell and organism level. The cytotoxic effect of CNTox, CNT-Dox, and CNT-FITC was analyzed on tumor cells in vitro (2-D, 3-D c...

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Bibliographic Details
Main Authors: Olena M. Perepelytsina, Andriy P. Ugnivenko, Alexey V. Dobrydnev, Olga N. Bakalinska, Andrii I. Marynin, Mychailo V. Sydorenko
Format: Article
Language:English
Published: SpringerOpen 2018-09-01
Series:Nanoscale Research Letters
Subjects:
Multi-walled carbon nanotubes
Nanotoxicity
Multicellular tumor spheroids
Doxorubicin
Hepatic function
Cell blood composition
Online Access:http://link.springer.com/article/10.1186/s11671-018-2689-9

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http://link.springer.com/article/10.1186/s11671-018-2689-9

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