Red blood cell eNOS is cardioprotective in acute myocardial infarction

Red blood cell eNOS is cardioprotective in acute myocardial infarction

Red blood cells (RBCs) were shown to transport and release nitric oxide (NO) bioactivity and carry an endothelial NO synthase (eNOS). However, the pathophysiological significance of RBC eNOS for cardioprotection in vivo is unknown. Here we aimed to analyze the role of RBC eNOS in the regulation of c...

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Bibliographic Details
Main Authors: Miriam M. Cortese-Krott, Tatsiana Suvorava, Francesca Leo, Sophia K. Heuser, Anthea LoBue, Junjie Li, Stefanie Becher, Rebekka Schneckmann, Tanu Srivrastava, Ralf Erkens, Georg Wolff, Joachim P. Schmitt, Maria Grandoch, Jon O. Lundberg, John Pernow, Brant E. Isakson, Eddie Weitzberg, Malte Kelm
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Redox Biology
Subjects:
Acute myocardial infarction
Nitric oxide synthase
Red blood cells
Cre/LoxP system
Ischemia/reperfusion injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001422

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http://www.sciencedirect.com/science/article/pii/S2213231722001422

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