Immune Checkpoint Glycoproteins Have Polymorphism: Are Monoclonal Antibodies Too Specific?

Since the 2018 Nobel prize in medicine was granted to the discovery of immune escape by cancer cells, billions of dollars have been spent on a new form of cancer immunotherapy called immune checkpoint inhibition (ICI). In this treatment modality, monoclonal antibodies (mAbs) are used to block cell-s...

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Bibliographic Details
Main Authors: Mehrsa Jalalizadeh, Reza Yadollahvandmiandoab, Leonardo Oliveira Reis
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/30/1/98