Rascaf: Improving Genome Assembly with RNA Sequencing Data

Abundant but short second-generation sequencing reads make assembly difficult, leading to fragmented genomes and gene annotations. Gene structure information from RNA sequences can be used to improve the completeness and contiguity of an assembly, but bioinformatics methods have been lacking. Rascaf...

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Bibliographic Details
Main Authors: Li Song, Dhruv S. Shankar, Liliana Florea
Format: Article
Language:English
Published: Wiley 2016-11-01
Series:The Plant Genome
Online Access:https://dl.sciencesocieties.org/publications/tpg/articles/9/3/plantgenome2016.03.0027