Self-immolative nanocapsules precisely regulate depressive neuronal microenvironment for synergistic antidepression therapy

Abstract Background Pharmacotherapy constitutes the first-line treatment for depression. However, its clinical use is hindered by several limitations, such as time lag, side effects, and narrow therapeutic windows. Nanotechnology can be employed to shorten the onset time by ensuring permeation acros...

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Bibliographic Details
Main Authors: Ziyao Liu, Bei Chen, Shijun Xiang, Shuo Hu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-023-02008-9