Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis

Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis

Among patients with obsessive-compulsive disorder (OCD), 65–85% manifest another psychiatric disorder concomitantly or at some other time point during their life. OCD is highly heritable, as are many of its comorbidities. A possible genetic heterogeneity of OCD in relation to its comorbid conditions...

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Bibliographic Details
Main Authors: Nora I. Strom, Jakob Grove, Sandra M. Meier, Marie Bækvad-Hansen, Judith Becker Nissen, Thomas Damm Als, Matthew Halvorsen, Merete Nordentoft, Preben B. Mortensen, David M. Hougaard, Thomas Werge, Ole Mors, Anders D. Børglum, James J. Crowley, Jonas Bybjerg-Grauholm, Manuel Mattheisen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
obsessive-compulsive disorder
major depression
attention-deficit/hyperactivity disorder
autism
comorbidity
polygenic risk score
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.711624/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.711624/full

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