Omega-3 fatty acid prevents the development of heart failure by changing fatty acid composition in the heart

Abstract Some clinical trials showed that omega-3 fatty acid (FA) reduced cardiovascular events, but it remains unknown whether omega-3 FA supplementation changes the composition of FAs and their metabolites in the heart and how the changes, if any, exert beneficial effects on cardiac structure and...

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Main Authors: Haruhiro Toko, Hiroyuki Morita, Masanori Katakura, Michio Hashimoto, Toshiyuki Ko, Satoshi Bujo, Yusuke Adachi, Kazutaka Ueda, Haruka Murakami, Masato Ishizuka, Jiaxi Guo, Chunxia Zhao, Takayuki Fujiwara, Hironori Hara, Norifumi Takeda, Eiki Takimoto, Osamu Shido, Mutsuo Harada, Issei Komuro
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-72686-0