Stereochemistry of Complex Marine Natural Products by Quantum Mechanical Calculations of NMR Chemical Shifts: Solvent and Conformational Effects on Okadaic Acid

Stereochemistry of Complex Marine Natural Products by Quantum Mechanical Calculations of NMR Chemical Shifts: Solvent and Conformational Effects on Okadaic Acid

Marine organisms are an increasingly important source of novel metabolites, some of which have already inspired or become new drugs. In addition, many of these molecules show a high degree of novelty from a structural and/or pharmacological point of view. Structure determination is generally achieve...

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Bibliographic Details
Main Authors: Humberto J. Domínguez, Guillermo D. Crespín, Adrián J. Santiago-Benítez, José A. Gavín, Manuel Norte, José J. Fernández, Antonio Hernández Daranas
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Marine Drugs
Subjects:
quantum mechanical calculations
nuclear magnetic resonance
chemical shifts
marine toxin
structure determination
stereochemistry
Online Access:http://www.mdpi.com/1660-3397/12/1/176

Internet

http://www.mdpi.com/1660-3397/12/1/176

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