Mice with humanized immune system as novel models to study HIV-associated pulmonary hypertension

Mice with humanized immune system as novel models to study HIV-associated pulmonary hypertension

People living with HIV and who receive antiretroviral therapy have a significantly improved lifespan, compared to the early days without therapy. Unfortunately, persisting viral replication in the lungs sustains chronic inflammation, which may cause pulmonary vascular dysfunction and ultimate life-t...

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Bibliographic Details
Main Authors: Valerie J. Rodriguez-Irizarry, Alina C. Schneider, Daniel Ahle, Justin M. Smith, Edu B. Suarez-Martinez, Ethan A. Salazar, Brianyell McDaniel Mims, Fahmida Rasha, Hanna Moussa, Naima Moustaïd-Moussa, Kevin Pruitt, Marcelo Fonseca, Mauricio Henriquez, Matthias A. Clauss, Matthew B. Grisham, Sharilyn Almodovar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
HIV
HIV-associated pulmonary hypertension
HIV-PH
HIV-PH Pulmonary hypertension
EMAP II
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.936164/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.936164/full

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