Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge.

Sublingual route offers a safer and more practical approach for delivering vaccines relative to other systemic and mucosal immunization strategies. Here we present evidence demonstrating protection against ovalbumin expressing B16 (B16-OVA) metastatic melanoma lung tumor formation by sublingual vacc...

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Bibliographic Details
Main Authors: Shailbala Singh, Guojun Yang, Kimberly S Schluns, Scott M Anthony, K Jagannadha Sastry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090001&type=printable