<named-content content-type="genus-species">Streptococcus pneumoniae</named-content> DNA Initiates Type I Interferon Signaling in the Respiratory Tract

<named-content content-type="genus-species">Streptococcus pneumoniae</named-content> DNA Initiates Type I Interferon Signaling in the Respiratory Tract

ABSTRACT The mucosal epithelium is the initial target for respiratory pathogens of all types. While type I interferon (IFN) signaling is traditionally associated with antiviral immunity, we demonstrate that the extracellular bacterial pathogen Streptococcus pneumoniae activates the type I IFN cascad...

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Bibliographic Details
Main Authors: Dane Parker, Francis J. Martin, Grace Soong, Bryan S. Harfenist, Jorge L. Aguilar, Adam J. Ratner, Katherine A. Fitzgerald, Christian Schindler, Alice Prince
Format: Article
Language:English
Published: American Society for Microbiology 2011-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00016-11

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https://journals.asm.org/doi/10.1128/mBio.00016-11

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