Old Dogs with New Tricks: Antiparasitic Potential of Structurally Diverse 5-Nitrofuran and 5-Nitrothiophene Imines and Acyl Hydrazones

Old Dogs with New Tricks: Antiparasitic Potential of Structurally Diverse 5-Nitrofuran and 5-Nitrothiophene Imines and Acyl Hydrazones

Miscellaneous imines and acyl hydrazones were prepared from 5-nitrofuraldehyde and 5-nitrothiophene-2-carboxaldehyde. Their activities against <i>Toxoplasma gondii</i> and <i>Leishmania major</i> parasites were evaluated. Promising antiparasitic effects and selectivities were...

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Bibliographic Details
Main Authors: Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Rainer Schobert, Bernhard Biersack
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Scientia Pharmaceutica
Subjects:
nitroarene drugs
neglected tropical diseases
leishmaniasis
toxoplasmosis
antiparasitic drugs
Online Access:https://www.mdpi.com/2218-0532/91/3/44

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https://www.mdpi.com/2218-0532/91/3/44

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