Reconstruction of a Global Transcriptional Regulatory Network for Control of Lipid Metabolism in Yeast by Using Chromatin Immunoprecipitation with Lambda Exonuclease Digestion

Reconstruction of a Global Transcriptional Regulatory Network for Control of Lipid Metabolism in Yeast by Using Chromatin Immunoprecipitation with Lambda Exonuclease Digestion

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ABSTRACT To build transcription regulatory networks, transcription factor binding must be analyzed in cells grown under different conditions because their responses and targets differ depending on environmental conditions. We performed whole-genome analysis of the DNA binding of five Saccharomyces c...

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Bibliographic Details
Main Authors: David Bergenholm, Guodong Liu, Petter Holland, Jens Nielsen
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSystems
Subjects:
ChIP-exo
transcriptional regulatory network
environmental response
lipid metabolic map
novel targets
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00215-17

Internet

https://journals.asm.org/doi/10.1128/mSystems.00215-17

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