Striatal CDK5 Regulates Cholinergic Neuron Activation and Dyskinesia-like Behaviors through BK Channels

Striatal CDK5 Regulates Cholinergic Neuron Activation and Dyskinesia-like Behaviors through BK Channels

Disturbance of the cholinergic system plays a crucial role in the pathological progression of neurological diseases that cause dyskinesia-like behaviors. However, the molecular mechanisms underlying this disturbance remain elusive. Here, we showed that cyclin-dependent kinase 5 (Cdk5) was reduced in...

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Bibliographic Details
Main Authors: Chu Tong, Peng-Xiang Min, Qian Zhang, Ru-Xin Gu, Yao-Hai Wen, Yi Shi, Yu-Huan Bao, Xiang Chen, Yi-Xuan Zhang, Xing-Feng Mao, Hao-Yang Yuan, Xiu-Xiu Liu, Takuya Sasaki, Li Zhang, Feng Han, Ying-Mei Lu
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0121

Internet

https://spj.science.org/doi/10.34133/research.0121

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