B-Cell Depletion Improves Islet Allograft Survival with Anti-CD45RB

A short course of anti-CD45RB leads to long-term islet allograft survival and donor-specific tolerance in approximately half of immunocompetent mice. We have previously demonstrated that anti-CD45RB antibody-mediated tolerance requires B-cells for cardiac allograft survival. We therefore asked wheth...

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Bibliographic Details
Main Authors: Kang Mi Lee, Heidi Yeh, Gaoping Zhao, Lingling Wei, Matthew O'connor, Ryan T. Stott, Julie Soohoo, Kyri Dunussi, Paolo Fiorina, Shaoping Deng, James F. Markmann M.D., Ph.D., James I. Kim
Format: Article
Language:English
Published: SAGE Publishing 2014-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X658962