Targeting a Novel G-Quadruplex in the <i>CARD11</i> Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group

Targeting a Novel G-Quadruplex in the <i>CARD11</i> Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group

The aggressive nature of the activated B cell such as (ABC) subtype of diffuse large B cell (DLBCL) is frequently associated with altered B cell Receptor (BCR) signaling through the activation of key components including the scaffolding protein, <i>CARD11</i>. Most inhibitors, such as ib...

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Bibliographic Details
Main Authors: Kennith Swafford, Baku Acharya, Ying-Zhi Xu, Thomas Raney, Mason McCrury, Debasmita Saha, Brendan Frett, Samantha Kendrick
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Genes
Subjects:
G-quadruplex
diffuse large B cell lymphoma
transcription analogs
Online Access:https://www.mdpi.com/2073-4425/13/7/1144

Internet

https://www.mdpi.com/2073-4425/13/7/1144

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