Mechanical stimulation controls osteoclast function through the regulation of Ca2+-activated Cl− channel Anoctamin 1

Mechanical stimulation controls osteoclast function through the regulation of Ca2+-activated Cl− channel Anoctamin 1

Abstract Mechanical force loading is essential for maintaining bone homeostasis, and unloading exposure can lead to bone loss. Osteoclasts are the only bone resorbing cells and play a crucial role in bone remodeling. The molecular mechanisms underlying mechanical stimulation-induced changes in osteo...

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Bibliographic Details
Main Authors: Weijia Sun, Yuheng Li, Jianwei Li, Yingjun Tan, Xinxin Yuan, Haoye Meng, Jianting Ye, Guohui Zhong, XiaoYan Jin, Zizhong Liu, Ruikai Du, Wenjuan Xing, Dingsheng Zhao, Jinping Song, Youyou Li, Junjie Pan, Yunzhang Zhao, Qi Li, Aiyuan Wang, Shukuan Ling, Rongji Dai, Yingxian Li
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04806-1

Internet

https://doi.org/10.1038/s42003-023-04806-1

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