Extracellular vesicle mitochondrial DNA levels are associated with race and mitochondrial DNA haplogroup

Summary: Circulating cell-free mitochondrial DNA (ccf-mtDNA) acts as a damage-associated molecular pattern molecule and may be cargo within extracellular vesicles (EVs). ccf-mtDNA and select mitochondrial DNA (mtDNA) haplogroups are associated with cardiovascular disease. We hypothesized that ccf-mt...

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Bibliographic Details
Main Authors: Anjali M. Byappanahalli, Victor Omoniyi, Nicole Noren Hooten, Jessica T. Smith, Nicolle A. Mode, Ngozi Ezike, Alan B. Zonderman, Michele K. Evans
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223028018