Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya.

<h4>Background</h4>Single nucleotide polymorphisms (SNPs) in the dhfr and dhps genes are associated with sulphadoxine-pyrimethamine (SP) treatment failure and gametocyte carriage. This may result in enhanced transmission of mutant malaria parasites, as previously shown for chloroquine re...

Full description

Bibliographic Details
Main Authors: Mayke J A M Oesterholt, Michael Alifrangis, Colin J Sutherland, Sabah A Omar, Patrick Sawa, Christina Howitt, Louis C Gouagna, Robert W Sauerwein, Teun Bousema
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19194499/?tool=EBI