Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives

Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives

Sirtuin 1 (SIRT1) is a NAD<sup>+</sup>-dependent deacetylase implicated in various biological and pathological processes, including cancer, diabetes, and cardiovascular diseases. In recent years, SIRT1-activating compounds have been demonstrated to exert cardioprotective effects. Therefo...

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Bibliographic Details
Main Authors: Giulia Bononi, Valentina Citi, Margherita Lapillo, Alma Martelli, Giulio Poli, Tiziano Tuccinardi, Carlotta Granchi, Lara Testai, Vincenzo Calderone, Filippo Minutolo
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
SIRT1
activators
cardioprotection
thiazoles
resveratrol
Online Access:https://www.mdpi.com/1420-3049/27/19/6535

Internet

https://www.mdpi.com/1420-3049/27/19/6535

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