Repositioned Drugs for Chagas Disease Unveiled via Structure-Based Drug Repositioning

Repositioned Drugs for Chagas Disease Unveiled via Structure-Based Drug Repositioning

Chagas disease, caused by the parasite <i>Trypanosoma cruzi</i>, affects millions of people in South America. The current treatments are limited, have severe side effects, and are only partially effective. Drug repositioning, defined as finding new indications for already approved drugs,...

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Bibliographic Details
Main Authors: Melissa F. Adasme, Sarah Naomi Bolz, Lauren Adelmann, Sebastian Salentin, V. Joachim Haupt, Adriana Moreno-Rodríguez, Benjamín Nogueda-Torres, Verónica Castillo-Campos, Lilián Yepez-Mulia, José A. De Fuentes-Vicente, Gildardo Rivera, Michael Schroeder
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
Chagas
<i>Trypanosoma cruzi</i>
drug repositioning
structural screening
non-covalent interactions
Online Access:https://www.mdpi.com/1422-0067/21/22/8809

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https://www.mdpi.com/1422-0067/21/22/8809

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